Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366558 | 0.92 | NPC1 (0.42) | NPC1ATMGAARXFP1CA12 | |
| SCHEMBL367749 | 0.91 | NPC1 (0.41) | NPC1ATMGAARXFP1CA12 | |
| SCHEMBL365272 | 0.91 | CA12 (0.42) | NPC1ATMGAARXFP1CA12 | |
| SCHEMBL366033 | 0.89 | NPC1 (0.40) | NPC1ATMGAARXFP1CA12 | |
| SCHEMBL366076 | 0.87 | CA12 (0.41) | NPC1ATMGAARXFP1CA12 | |
| SCHEMBL367765 | 0.83 | NPC1 (0.43) | NPC1ATMGAARXFP1KDM4E | |
| SCHEMBL365020 | 0.81 | BAZ2B (0.43) | NPC1ATMGAARXFP1KDM4E | |
| SCHEMBL366019 | 0.81 | STS (0.41) | NPC1ATMGAARXFP1CA12 | |
| SCHEMBL366820 | 0.81 | IDO1 (0.43) | GAACA12CA1CA2CA7 | |
| SCHEMBL367733 | 0.80 | KMT2A (0.38) | NPC1ATMGAARXFP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |