Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654254 | 0.97 | EPHX2 (0.46) | EPHX2RAB9AGAALMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL3657679 | 0.90 | RAB9A (0.46) | RAB9AGAALMNAMAPTNPC1 | |
| SCHEMBL3652812 | 0.89 | PDE4D (0.40) | EPHX2RAB9AGAALMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL3657528 | 0.86 | RXFP1 (0.37) | RAB9ARXFP1ALDH1A1CYP1A2CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL3653064 | 0.84 | KDM4E (0.42) | RAB9AGAALMNAMAPTNPC1 | |
| SCHEMBL3655451 | 0.83 | TSHR (0.40) | GAARXFP1ALDH1A1CYP2C19KMT2A | |
| Trifluoroacetic Acid SCHEMBL3657556 | 0.82 | HSP90AA1 (0.45) | RAB9AGAALMNAMAPTRXFP1 | |
| Trifluoroacetic Acid SCHEMBL3659571 | 0.81 | RAB9A (0.45) | RAB9AMAPTNPC1ALDH1A1KMT2A | |
| SCHEMBL3658110 | 0.81 | KDM4E (0.44) | RAB9AGAALMNAMAPTNPC1 | |
| SCHEMBL3653093 | 0.80 | CYP1A2 (0.36) | RAB9ACYP1A2CYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |