Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3659571 | 0.91 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2KMT2ATP53 | |
| Trifluoroacetic Acid SCHEMBL3652246 | 0.90 | EPHX2 (0.43) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL3657556 | 0.90 | HSP90AA1 (0.45) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3654254 | 0.86 | EPHX2 (0.46) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3657680 | 0.84 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL3653109 | 0.84 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3650124 | 0.83 | HSP90AA1 (0.50) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL3654963 | 0.83 | — | — | |
| Trifluoroacetic Acid SCHEMBL3655787 | 0.83 | MLYCD (0.46) | RAB9ANPC1MEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL3653624 | 0.81 | KDM4E (0.40) | TP53KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |