Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653079 | 0.94 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| Trifluoroacetic Acid SCHEMBL3656228 | 0.89 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL3655451 | 0.85 | TSHR (0.40) | SMN1; SMN2GAAALDH1A1GFERKMT2A | |
| Trifluoroacetic Acid SCHEMBL3654963 | 0.85 | — | — | |
| Trifluoroacetic Acid SCHEMBL3659571 | 0.84 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| Trifluoroacetic Acid SCHEMBL3657679 | 0.84 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| Trifluoroacetic Acid SCHEMBL3657521 | 0.83 | MEN1 (0.42) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| Trifluoroacetic Acid SCHEMBL3653624 | 0.83 | KDM4E (0.40) | MAPTTP53ALDH1A1 | |
| SCHEMBL3658339 | 0.82 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| Trifluoroacetic Acid SCHEMBL3654346 | 0.81 | JAK3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |