Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 7/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SCN2B | O60939 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366253 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDRORCLMNA | |
| SCHEMBL364816 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDRORC | |
| SCHEMBL366210 | 0.89 | HPGD (0.47) | ALDH1A1KDM4EHPGDLMNAEGFR | |
| SCHEMBL366978 | 0.88 | SCN9A (0.45) | ALDH1A1KDM4EHPGDSCN2BSCN1A | |
| SCHEMBL366383 | 0.86 | HPGD (0.40) | KDM4EHPGDLMNASMN1; SMN2HDAC6 | |
| SCHEMBL366060 | 0.83 | LMNA (0.42) | ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL365520 | 0.82 | POLB (0.46) | ALDH1A1KDM4EHPGDLMNAEGFR | |
| SCHEMBL365440 | 0.81 | MAPT (0.41) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL367569 | 0.80 | SRC (0.46) | ALDH1A1KDM4EHPGDRORCNR4A2 | |
| SCHEMBL366442 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDNR4A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |