Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 4/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365703 | 0.85 | KMT2A (0.50) | KMT2AGAAKCNK3KCNH2AURKA | |
| SCHEMBL366362 | 0.81 | SMN1; SMN2 (0.54) | KMT2AKDM4EALDH1A1LMNAALOX12 | |
| SCHEMBL364303 | 0.79 | KMT2A (0.46) | KMT2AGAAKDM4EALDH1A1LMNA | |
| SCHEMBL24273183 | 0.77 | KCNK3 (0.56) | KMT2AGAAKCNK3KCNH2KDM4E | |
| SCHEMBL24273393 | 0.76 | PTGER4 (0.64) | KMT2AGAAKCNK3KCNH2PTAFR | |
| SCHEMBL24273319 | 0.74 | LMNA (0.52) | KCNK3KCNH2PTAFRKDM4EALDH1A1 | |
| SCHEMBL365565 | 0.73 | KMT2A (0.52) | KMT2AGAAKDM4EALDH1A1LMNA | |
| SCHEMBL24273219 | 0.72 | PTGER4 (0.65) | KMT2AGAAPTAFRALDH1A1MEN1 | |
| SCHEMBL365014 | 0.71 | KDM4E (0.48) | KMT2AGAAKDM4EALDH1A1HTT | |
| SCHEMBL24273468 | 0.71 | MAPT (0.52) | KMT2AKDM4EALDH1A1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |