Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248938 | 0.96 | TSHR (0.54) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| Potassium Ion SCHEMBL7626089 | 0.81 | TSHR (0.50) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| Potassium Ion SCHEMBL28817684 | 0.81 | TSHR (0.50) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL454340 | 0.79 | TSHR (0.58) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL31228319 | 0.78 | TSHR (0.56) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| Potassium SCHEMBL9499549 | 0.78 | TSHR (0.56) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL27481943 | 0.78 | TSHR (0.56) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL1775597 | 0.77 | TSHR (0.50) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL31441111 | 0.77 | TSHR (0.50) | TSHRTGM2CYP2C19ALDH1A1MAPK1 | |
| Lithium Ion SCHEMBL28817701 | 0.77 | TSHR (0.50) | TSHRTGM2CYP2C19ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271797-B1 | SILVER HALIDE COLOR LIGHT SENSITIVE ELEMENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-05-26 | — | — | EP | claimed |
| US-4990435-A | Stable polymeric coating | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-02-05 | — | — | US | claimed |
| EP-0226129-B1 | SILVER HALIDE PHOTOGRAPHIC ELEMENT, PHOTOGRAPHIC COATING COMPOSITION AND PROCESS TO PREPARE AN AQUEOUS DISPERSION OF A HYDROPHOBIC COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-23 | — | — | EP | claimed |
| US-4822728-A | CONTROLLED SMEARING OF IMAGE-FORMING DYE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-04-18 | — | — | US | claimed |
| EP-0271797-A2 | Silver halide color light sensitive elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-06-22 | — | — | EP | claimed |
| EP-0226129-A2 | Silver halide photographic element, photographic coating composition and process to prepare an aqueous dispersion of a hydrophobic compound | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-06-24 | — | — | EP | claimed |
| EP-1781717-B1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL AG & CO KGAA (DE) | 2012-11-07 | — | — | EP | disclosed |
| EP-2215134-A2 | REDUCTION OF THE FORMATION OF BIOFILM BY MEANS OF MULTIFUNCTIONAL COPOLYMERS | Henkel AG & Co. KGaA (DE) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009071451-A2 | REDUCTION OF THE FORMATION OF BIOFILM BY MEANS OF MULTIFUNCTIONAL COPOLYMERS | HENKEL AG & CO. KGAA (DE) | 2009-06-11 | — | — | WO | disclosed |
| EP-1781717-A1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006005358-A1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-01-19 | — | — | WO | disclosed |