SCHEMBL3657922

SCHEMBL3657922

CCCCCC=CCOc1cccc(NC)c1F

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 3/20 0.41
CYSLTR1 Q9Y271 3/20 0.41
PPARA Q07869 1/20 0.34
POLM Q9NP87 1/20 0.34
POLK Q9UBT6 1/20 0.34
POLL Q9UGP5 1/20 0.34
POLH Q9Y253 1/20 0.34
PPARG P37231 1/20 0.33
PTGS2 P35354 1/20 0.33
PTPN1 P18031 1/20 0.33
SOAT2 O75908 1/20 0.33
SOAT1 P35610 1/20 0.33
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3771170 1.00 CYSLTR2 (0.41) CYSLTR2CYSLTR1PPARAPOLMPOLK
SCHEMBL3763438 0.96 CYSLTR2 (0.37) CYSLTR2CYSLTR1PPARAPOLMPOLK
SCHEMBL3659528 0.96 CYSLTR2 (0.37) CYSLTR2CYSLTR1PPARAPOLMPOLK
SCHEMBL3660887 0.91 CTSL (0.35) CYSLTR2CYSLTR1CTSLCTSSCTSK
SCHEMBL3769102 0.91 CTSL (0.35) CYSLTR2CYSLTR1CTSLCTSSCTSK
SCHEMBL3660872 0.85 PTPN1 (0.38) PPARAPPARGPTGS2PTPN1
SCHEMBL3764580 0.85 PTPN1 (0.38) PPARAPPARGPTGS2PTPN1
SCHEMBL3659486 0.85 CTSS (0.34) CTSLCTSSCTSK
SCHEMBL3768078 0.85 CTSS (0.34) CTSLCTSSCTSK
SCHEMBL3662544 0.84 L3MBTL1 (0.38) PPARGPTGS2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 CYSLTR2 2358/4885CYSLTR1 2654/4885PPARA 1791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.