SCHEMBL3769102

SCHEMBL3769102

CCC/C=C/COc1cccc(NC)c1F

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
APP P05067 1/20 0.33
CYSLTR2 Q9NS75 2/20 0.32
CYSLTR1 Q9Y271 2/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3660887 1.00 CTSL (0.35) CTSLCTSSCTSKAPPCYSLTR2
SCHEMBL3659528 0.92 CYSLTR2 (0.37) CTSLCTSSCTSKAPPCYSLTR2
SCHEMBL3763438 0.92 CYSLTR2 (0.37) CTSLCTSSCTSKAPPCYSLTR2
SCHEMBL3657922 0.91 CYSLTR2 (0.41) CTSLCTSSCTSKCYSLTR2CYSLTR1
SCHEMBL3771170 0.91 CYSLTR2 (0.41) CTSLCTSSCTSKCYSLTR2CYSLTR1
SCHEMBL3766152 0.89 PTPN1 (0.35) APPALDH1A1
SCHEMBL3660391 0.89 PTPN1 (0.35) APPALDH1A1
SCHEMBL3659486 0.88 CTSS (0.34) CTSLCTSSCTSKAPPALDH1A1
SCHEMBL3768078 0.88 CTSS (0.34) CTSLCTSSCTSKAPPALDH1A1
SCHEMBL3662544 0.87 L3MBTL1 (0.38) APPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 CTSL 4124/4885CTSS 2078/4885CTSK 3257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.