SCHEMBL3763438

SCHEMBL3763438

CCCC/C=C/COc1cccc(NC)c1F

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 5/20 0.37
CYSLTR1 Q9Y271 5/20 0.37
PTGS2 P35354 1/20 0.36
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
KMT2A Q03164 1/20 0.33
PPARG P37231 1/20 0.32
PTPN1 P18031 1/20 0.32
APP P05067 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
POLM Q9NP87 1/20 0.31
POLK Q9UBT6 1/20 0.31
POLL Q9UGP5 1/20 0.31
POLH Q9Y253 1/20 0.31
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3659528 1.00 CYSLTR2 (0.37) CYSLTR2CYSLTR1PTGS2CTSLCTSS
SCHEMBL3657922 0.96 CYSLTR2 (0.41) CYSLTR2CYSLTR1PTGS2CTSLCTSS
SCHEMBL3771170 0.96 CYSLTR2 (0.41) CYSLTR2CYSLTR1PTGS2CTSLCTSS
SCHEMBL3769102 0.92 CTSL (0.35) CYSLTR2CYSLTR1CTSLCTSSCTSK
SCHEMBL3660887 0.92 CTSL (0.35) CYSLTR2CYSLTR1CTSLCTSSCTSK
SCHEMBL3660872 0.89 PTPN1 (0.38) PTGS2KMT2APPARGPTPN1MAPT
SCHEMBL3764580 0.89 PTPN1 (0.38) PTGS2KMT2APPARGPTPN1MAPT
SCHEMBL3659486 0.86 CTSS (0.34) CTSLCTSSCTSKAPP
SCHEMBL3768078 0.86 CTSS (0.34) CTSLCTSSCTSKAPP
SCHEMBL3662544 0.85 L3MBTL1 (0.38) PTGS2KMT2APPARGPTPN1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 CYSLTR2 2358/4885CYSLTR1 2654/4885PTGS2 3626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.