SCHEMBL3658280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19671506	0.86	L3MBTL1 (0.50)	KMT2ATSHR
	SCHEMBL435251	0.86	CYP1A2 (0.50)	MIFKMT2A
	SCHEMBL18800484	0.85	LY96 (0.43)	ESR1ESR2MIFMDM4MDM2
	SCHEMBL3662079	0.82	ESR1 (0.61)	ESR1ESR2MIFKMT2ANPSR1
	SCHEMBL3870170	0.82	ESR1 (0.61)	ESR1ESR2MIFKMT2ANPSR1
	SCHEMBL13078733	0.82	ESR1 (0.61)	ESR1ESR2MIFKMT2ANPSR1
	SCHEMBL3718057	0.81	LTA4H (0.61)	NPC1RAB9AMMP9
	SCHEMBL20796956	0.81	ESR1 (0.59)	ESR1ESR2MIFKMT2ANPSR1
	SCHEMBL3965849	0.79	ESR1 (0.58)	ESR1ESR2MIFKMT2ANPSR1
	SCHEMBL27865676	0.79	ESR1 (0.54)	ESR1ESR2MIFKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.