Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109289 | 0.85 | FTO (0.78) | FTOUSP2L3MBTL1CFTRGOPC | |
| SCHEMBL31435692 | 0.85 | FTO (0.78) | FTOUSP2L3MBTL1CFTRGOPC | |
| SCHEMBL7970059 | 0.85 | USP2 (0.76) | USP2L3MBTL1ABCB1CFTRPAX8 | |
| SCHEMBL24158027 | 0.84 | FTO (0.58) | FTOUSP2L3MBTL1ATMMEN1 | |
| SCHEMBL29483446 | 0.82 | ABCB1 (0.63) | FTOUSP2L3MBTL1ABCB1CFTR | |
| SCHEMBL14627720 | 0.82 | ABCB1 (0.63) | FTOUSP2L3MBTL1ABCB1CFTR | |
| SCHEMBL10293762 | 0.81 | USP2 (0.53) | FTOUSP2L3MBTL1ABCB1CFTR | |
| SCHEMBL18972336 | 0.80 | FTO (0.74) | FTOUSP2L3MBTL1CFTRGOPC | |
| SCHEMBL21129885 | 0.78 | FTO (0.74) | FTOUSP2L3MBTL1CFTRGOPC | |
| SCHEMBL25829597 | 0.78 | FTO (0.70) | FTOUSP2L3MBTL1CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230120665-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | LIFE TECHNOLOGIES CORP (US) | 2023-04-20 | — | — | US | disclosed |
| US-20190242912-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation | 2019-08-08 | — | — | US | disclosed |
| US-20170067918-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation | 2017-03-09 | — | — | US | disclosed |
| US-9476892-B2 | Composition and method for measuring thallium influx and efflux | Life Technologies Corporation (US) | 2016-10-25 | — | — | US | disclosed |
| US-20150104823-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation | 2015-04-16 | — | — | US | disclosed |
| EP-2201367-B1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | LIFE TECHNOLOGIES CORP (US) | 2013-03-20 | — | — | EP | disclosed |
| EP-2562543-A1 | Composition and method for measuring thallium influx and efflux | Life Technologies Corporation (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20100279314-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation | 2010-11-04 | — | — | US | disclosed |
| EP-2201367-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009052183-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | INVITROGEN CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |