Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 14/20 | 0.42 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.42 |
| ▸ | SCN2B | O60939 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365520 | 0.89 | POLB (0.46) | ALDH1A1MAPTHPGDFLT1FLT4 | |
| SCHEMBL365931 | 0.85 | MAPT (0.47) | ALDH1A1MAPTHPGDFLT1FLT4 | |
| SCHEMBL366978 | 0.81 | SCN9A (0.45) | ALDH1A1HPGDSCN2BSCN1ASCN1B | |
| SCHEMBL366980 | 0.80 | PTGER4 (0.41) | FLT1FLT4KDRPTGER4ALKBH2 | |
| SCHEMBL365441 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDSCN2BSCN1ASCN1B | |
| SCHEMBL366383 | 0.78 | HPGD (0.40) | MAPTHPGDPTGER4 | |
| SCHEMBL366253 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDPTGER4 | |
| SCHEMBL366210 | 0.76 | HPGD (0.47) | ALDH1A1MAPTHPGDPTGER4 | |
| SCHEMBL364816 | 0.75 | ALDH1A1 (0.41) | ALDH1A1HPGDPTGER4 | |
| SCHEMBL367569 | 0.74 | SRC (0.46) | ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |