Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 15/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364821 | 0.90 | ADAM17 (0.41) | PTGER4 | |
| SCHEMBL366979 | 0.88 | KMT2A (0.45) | FLT1FLT4KDRFBP1ALKBH2 | |
| SCHEMBL364828 | 0.84 | MCL1 (0.37) | MCL1 | |
| SCHEMBL366344 | 0.83 | PSEN1 (0.39) | MCL1 | |
| SCHEMBL367074 | 0.81 | LMNA (0.39) | PTGER4MCL1 | |
| SCHEMBL364894 | 0.81 | PSEN1 (0.39) | PTGER4 | |
| SCHEMBL365932 | 0.80 | ALDH1A1 (0.48) | PTGER4FLT1FLT4KDRFBP1 | |
| SCHEMBL367542 | 0.79 | PSEN1 (0.42) | MCL1 | |
| SCHEMBL365499 | 0.79 | P4HTM (0.38) | PTGER4MCL1 | |
| SCHEMBL364820 | 0.79 | KMT2A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |