Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.37 |
| ▸ | KDM5A | P29375 | 7/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560704 | 0.88 | KMT2A (0.46) | KMT2AMEN1KDM4CKDM5ALTA4H | |
| SCHEMBL11435258 | 0.86 | KMT2A (0.45) | KMT2AMEN1KDM4CKDM5ALTA4H | |
| Trifluoroacetic Acid SCHEMBL4552800 | 0.81 | CHRM2 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21048742 | 0.81 | KMT2A (0.38) | KMT2AMEN1KDM4CKDM5ALTA4H | |
| Trifluoroacetic Acid SCHEMBL3559072 | 0.78 | HTR5A (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Trifluoroacetic Acid SCHEMBL3086474 | 0.77 | KDM4C (0.45) | KMT2AMEN1KDM4CKDM5AKDM5C | |
| SCHEMBL718216 | 0.77 | KMT2A (0.56) | KMT2AMEN1KDM4CKDM5ALTA4H | |
| SCHEMBL11439889 | 0.76 | KMT2A (0.52) | KMT2AMEN1KDM4CKDM5ALTA4H | |
| Trifluoroacetic Acid SCHEMBL8201988 | 0.75 | LMNA (0.48) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL11239382 | 0.75 | KMT2A (0.54) | KMT2AMEN1KDM4CKDM5ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217621-B1 | INSULIN DERIVATIVE | NOVO NORDISK AS (DK) | 2015-04-22 | — | — | EP | disclosed |
| US-8710000-B2 | Insulin derivative | NOVO NORDISK A/S (DK) | 2014-04-29 | — | — | US | disclosed |
| US-20100279931-A1 | Insulin Derivative | NOVO NORDISK A/S | 2010-11-04 | — | — | US | disclosed |
| EP-2217621-A1 | INSULIN DERIVATIVE | Novo Nordisk A/S (DK) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009060071-A1 | INSULIN DERIVATIVE | NOVO NORDISK A/S (DK) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058330-A1 | Insulin derivative | NOVO NORDISK A/S (DK) | 2009-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279931-A1 | Insulin Derivative | IAPP, INSR, GPR119 | KMT2A 4687/4885MEN1 690/4885KDM4C 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.