Sugi Predict

Sugi Predict / Compounds / SCHEMBL366122

SCHEMBL366122

SCHEMBL366122

Cc1ccc(C=C[N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 13/20 1.00
▸ EGFR P00533 2/20 0.64
▸ ALDH1A1 P00352 3/20 0.63
▸ LMNA P02545 3/20 0.63
▸ MAPT P10636 2/20 0.63
▸ SMN1; SMN2 Q16637 2/20 0.63
▸ MEN1 O00255 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ S1PR4 O95977 1/20 0.56
▸ HSP90AA1 P07900 1/20 0.56
▸ HPGD P15428 1/20 0.56
▸ S1PR1 P21453 1/20 0.56
▸ MAPK1 P28482 1/20 0.56
▸ CCR6 P51684 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ TLR9 Q9NR96 1/20 0.56
▸ TLR4 O00206 1/20 0.55
▸ TLR2 O60603 1/20 0.55
▸ ABL1 P00519 1/20 0.53
▸ ABL2 P42684 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366121 1.00 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL6910818 0.89 FBP1 (0.78) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL6910815 0.89 FBP1 (0.78) FBP1EGFRALDH1A1LMNAMAPT
(2-Nitrovinyl)Benzene SCHEMBL28961549 0.80 FBP1 (0.73) FBP1EGFRALDH1A1LMNAMAPT
Hexamethylbenzene SCHEMBL29275075 0.79 FBP1 (0.84) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL7412213 0.78 FBP1 (0.67) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL421633 0.78 FBP1 (0.64) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL2077031 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL102630 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT
SCHEMBL1681205 0.78 FBP1 (1.00) FBP1EGFRALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115025073-B Application of benzol nitro-compound serving as quorum sensing inhibitor in non-classical antibacterial activity 海南大学 2024-05-07 — — CN claimed
CN-115073350-B Preparation method of eremophilone 苏州富士莱医药股份有限公司 2023-09-12 — — CN claimed
CN-113943242-B Preparation method of polysubstituted pyrrole compound 浙江工业大学 2023-08-15 — — CN claimed
CN-115073350-A Preparation method of erexib 苏州富士莱医药股份有限公司 2022-09-20 — — CN claimed
CN-111116613-B Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof 湘潭大学 2021-04-23 — — CN claimed
CN-108912030-A A kind of synthetic method of imrecoxib 苏州富士莱医药股份有限公司 2018-11-30 — — CN claimed
CN-103848830-B A kind of simple and easy method of synthesis imidazo [1,2-α] pyridine derivate 淮阴师范学院 2016-08-03 — — CN claimed
EP-2982368-A1 Small molecule compounds displacing focal adhesion core components Universität Konstanz (DE) 2016-02-10 — — EP claimed
CN-102115446-B Method for catalytically synthesizing chiral curcumin analogs UNIV EAST CHINA SCIENCE & TECH 2014-05-07 — — CN claimed
CN-101628904-B Synthesis method of 2-nitro-3-aryl-2,3,5,7-tetrahydrobenzofuran-4-one derivative UNIV SOOCHOW 2012-04-25 — — CN claimed
CN-101343263-B Method for synthesizing 5-nitro-4, 5-dihydrofuran derivative UNIV SOOCHOW 2012-04-04 — — CN claimed
CN-101628904-A Synthesis method of 2-nitro-3-aryl-2,3,5,7-tetrahydrobenzofuran-4-one derivative UNIV SOOCHOW 2010-01-20 — — CN claimed
CN-101343263-A Method for synthesis of 5-nitryl-4, 5-dihydrofuran derivant UNIV SOOCHOW (CN) 2009-01-14 — — CN claimed
US-12612411-B1 Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins INSTITUT PASTEUR (FR) 2026-04-28 — — US disclosed
US-12576164-B2 Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins INSTITUT PASTEUR (FR) 2026-03-17 — — US disclosed
US-12568963-B2 Compounds and compositions for nematode treatment IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-03-10 — — US disclosed
US-4656298-A MUSCLE RELAXANTS, STIMULANTS, ANALGESICS, ANTICONVULSANTS, ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1987-04-07 — — US disclosed
US-4442264-A UNSATURATED AROMATIC NITRO OR CHLORINE COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1984-04-10 — — US disclosed
EP-0094525-A2 Grafted rubber for the modification of thermoplastic moulding compositions BAYER AG (DE) 1983-11-23 — — EP disclosed
US-3931220-A FUNGICIDE, BACTERICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576164-B2 Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins LUC7L2, HLCS, LANCL1 FBP1 1407/4885EGFR 3403/4885ALDH1A1 659/4885
US-12568963-B2 Compounds and compositions for nematode treatment MASTL, FBXL19, SRMS FBP1 2416/4885EGFR 495/4885ALDH1A1 4851/4885
US-12612411-B1 Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins LUC7L2, MRPL21, CRY1 FBP1 794/4885EGFR 3591/4885ALDH1A1 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.