Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666194 | 0.78 | MAPT (0.47) | KDM4EHPGDALDH1A1LMNAKMT2A | |
| SCHEMBL6518530 | 0.77 | PTGS1 (0.51) | HPGDALDH1A1LMNAPTGS1KMT2A | |
| SCHEMBL17697649 | 0.68 | BACE1 (0.49) | HSD17B10KDM4EHPGDALDH1A1KMT2A | |
| SCHEMBL6955861 | 0.68 | ALDH1A1 (0.49) | HSD17B10KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL13760654 | 0.68 | MAPT (0.44) | HSD17B10KDM4EHPGDALDH1A1NR4A2 | |
| SCHEMBL5282842 | 0.67 | L3MBTL1 (0.47) | HSD17B10KDM4EHPGDALDH1A1KMT2A | |
| SCHEMBL21587530 | 0.67 | PTGS1 (0.54) | HPGDALDH1A1LMNAPTGS1KMT2A | |
| SCHEMBL6938651 | 0.66 | HSD17B10 (0.47) | HSD17B10KDM4EHPGDALDH1A1PTGS1 | |
| Biphenyl SCHEMBL27492413 | 0.66 | TSHR (0.52) | HSD17B10KDM4EHPGDALDH1A1KMT2A | |
| SCHEMBL3667374 | 0.66 | MEN1 (0.40) | KDM4EALDH1A1NR4A2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240461-A1 | SUBSTITUTED FURANS AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009097991-A1 | SUBSTITUTED FURANS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-08-13 | — | — | WO | disclosed |