SCHEMBL366308

SCHEMBL366308

Brc1ccc(-c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
MAPK1 P28482 2/20 1.00
TDP1 Q9NUW8 2/20 0.62
NPC1 O15118 1/20 0.62
NFKB1 P19838 1/20 0.62
RAB9A P51151 1/20 0.62
NFKB2 Q00653 1/20 0.62
RELA Q04206 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
CYP2A6 P11509 1/20 0.53
NR1H4 Q96RI1 1/20 0.52
TAAR1 Q96RJ0 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
DGAT1 O75907 1/20 0.48
NR1H2 P55055 1/20 0.48
NR1H3 Q13133 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12367607 1.00 ALDH1A1 (1.00) ALDH1A1MAPK1TDP1NPC1NFKB1
Benzene SCHEMBL28146964 1.00 ALDH1A1 (1.00) ALDH1A1MAPK1TDP1NPC1NFKB1
Biphenyl SCHEMBL28399886 1.00 ALDH1A1 (1.00) ALDH1A1MAPK1TDP1NPC1NFKB1
SCHEMBL4691 1.00 ALDH1A1 (1.00) ALDH1A1MAPK1TDP1NPC1NFKB1
SCHEMBL18270367 1.00 ALDH1A1 (1.00) ALDH1A1MAPK1TDP1NPC1NFKB1
SCHEMBL25374262 1.00 ALDH1A1 (1.00) ALDH1A1MAPK1TDP1NPC1NFKB1
SCHEMBL17277082 1.00 ALDH1A1 (1.00) ALDH1A1MAPK1TDP1NPC1NFKB1
Water SCHEMBL5359213 0.97 ALDH1A1 (0.94) ALDH1A1MAPK1TDP1NPC1NFKB1
SCHEMBL28539439 0.97 ALDH1A1 (0.94) ALDH1A1MAPK1TDP1NPC1NFKB1
SCHEMBL3819507 0.97 ALDH1A1 (0.94) ALDH1A1MAPK1TDP1NPC1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106866347-B 2, 6-dimethyl-p-quaterphenyl and preparation method and application thereof 南华大学 2020-05-05 CN claimed
EP-0396943-B1 Optical storage medium and storage process NIPPON TELEGRAPH & TELEPHONE (JP) 1995-07-05 EP claimed
US-5124944-A OPTICAL STORAGE MEDIUM AND STORAGE PROCESS NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-23 US claimed
EP-0396943-A2 Optical storage medium and storage process NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1990-11-14 EP claimed
JP-5112501-A None JP disclosed
US-12635408-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-19 US disclosed
US-12583843-B2 Organic light-emitting device, method for manufacturing same, and composition for organic material layer of organic light-emitting device LT MATERIALS CO., LTD. (KR) 2026-03-24 US disclosed
US-20260070916-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2026-03-12 US disclosed
US-12543495-B2 Composition, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2026-02-03 US disclosed
EP-4095124-B1 ARYLAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2025-12-24 EP disclosed
US-20250333380-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO.,LTD. (JP) 2025-10-30 US disclosed
EP-3813138-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-08-27 EP disclosed
US-6670193-B2 Coupling with organometallic compound; emission light RESEARCH CORPORATION TECHNOLOGIES, INC. 2003-12-30 US disclosed
US-6479650-B1 Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same RESEARCH CORPORATION TECHNOLOGIES, INC. 2002-11-12 US disclosed
US-20020160411-A1 Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 2002-10-31 US disclosed
WO-2001044220-A2 FLUORESCENT NUCLEOSIDE ANALOGS AND COMBINATORIAL FLUOROPHORE ARRAYS COMPRISING SAME RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 2001-06-21 WO disclosed
EP-0396943-B1 Optical storage medium and storage process NIPPON TELEGRAPH & TELEPHONE (JP) 1995-07-05 EP disclosed
JP-H05112501-A BUTADIENE DERIVATIVE AND ELECTROPH0T0GRAPHIC PHOTORECEPTOR USING THE SAME MITA IND CO LTD 1993-05-07 JP disclosed
US-5124944-A OPTICAL STORAGE MEDIUM AND STORAGE PROCESS NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-23 US disclosed
EP-0126883-B1 LIQUID CRYSTALLINE CYCLOHEXYLBENZENE DERIVATIVES, THEIR PREPARATION AND THE LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) 1987-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020160411-A1 Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same DERA, FBL, DUT ALDH1A1 1698/4885MAPK1 1605/4885TDP1 253/4885
US-20260070916-A1 ORGANIC LIGHT EMITTING DEVICE ORC3, NR2E3, ARRB1 ALDH1A1 271/4885MAPK1 2465/4885TDP1 4065/4885
US-20250333380-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME ARSA, AHR, AOC2 ALDH1A1 292/4885MAPK1 598/4885TDP1 3703/4885
US-12583843-B2 Organic light-emitting device, method for manufacturing same, and composition for organic material layer of organic light-emitting device OXER1, RPL22, POR ALDH1A1 908/4885MAPK1 2383/4885TDP1 3876/4885
US-12543495-B2 Composition, organic optoelectronic device and display device NR2E3, OXER1, ACVRL1 ALDH1A1 47/4885MAPK1 413/4885TDP1 3754/4885
US-12635408-B2 Organic electroluminescence device and amine compound for organic electroluminescence device LEF1, MLLT1, NAP1L1 ALDH1A1 78/4885MAPK1 410/4885TDP1 1267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.