Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899684 | 0.83 | MMP8 (0.39) | MMP8ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1396438 | 0.82 | PRKCA (0.44) | MMP8ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1639936 | 0.82 | PRKCA (0.44) | MMP8ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL367661 | 0.81 | — | — | |
| SCHEMBL18856324 | 0.79 | MMP8 (0.39) | MMP8ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1972396 | 0.78 | MEN1 (0.39) | MMP8KMT2ALMNAPRKCAMEN1 | |
| SCHEMBL12386545 | 0.78 | CYP4F2 (0.44) | MMP8ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL2242736 | 0.78 | CYP4F2 (0.44) | MMP8ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL19812421 | 0.77 | MMP8 (0.36) | MMP8ALDH1A1KMT2ALMNAHSD17B10 | |
| SCHEMBL25082833 | 0.76 | ALDH1A1 (0.34) | MMP8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016072-A1 | HARDENER FOR SILICONE RUBBER MATERIALS | NITRO-CHEME ASCHAU GmbH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016072-A1 | HARDENER FOR SILICONE RUBBER MATERIALS | HACD2, HACD3, ITGA2 | MMP8 2464/4885ALDH1A1 559/4885KMT2A 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.