Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366851 | 0.92 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2ACNR2MEN1 | |
| SCHEMBL366612 | 0.92 | ACHE (0.38) | KMT2ASIGMAR1ACHE | |
| SCHEMBL365925 | 0.92 | ACHE (0.42) | ACHE | |
| SCHEMBL365837 | 0.91 | CNR2 (0.37) | ALDH1A1MAPTKMT2ACNR2MEN1 | |
| SCHEMBL365915 | 0.90 | S1PR3 (0.37) | MAPTKMT2ACNR2HTTPLA2G4A | |
| SCHEMBL366816 | 0.86 | KMT2A (0.37) | ALDH1A1MAPTKMT2ACNR2MEN1 | |
| SCHEMBL365786 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AMEN1ADORA3 | |
| SCHEMBL365189 | 0.85 | ACHE (0.37) | ALDH1A1CNR2SIGMAR1ACHE | |
| SCHEMBL366481 | 0.85 | ACHE (0.39) | ACHE | |
| SCHEMBL365169 | 0.84 | ACHE (0.41) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |