Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366900 | 0.93 | S1PR3 (0.39) | S1PR3PLA2G4AACHENPC1RAB9A | |
| SCHEMBL366612 | 0.91 | ACHE (0.38) | S1PR3ACHESMN1; SMN2KMT2A | |
| SCHEMBL366374 | 0.90 | ALDH1A1 (0.38) | PLA2G4AACHEKMT2ACNR2MAPT | |
| SCHEMBL365925 | 0.84 | ACHE (0.42) | ACHE | |
| SCHEMBL365189 | 0.83 | ACHE (0.37) | S1PR3ACHESMN1; SMN2CNR2 | |
| SCHEMBL365216 | 0.82 | ACHE (0.36) | S1PR3ACHENPC1RAB9AKMT2A | |
| SCHEMBL366851 | 0.82 | ALDH1A1 (0.38) | S1PR3PLA2G4AKMT2ACNR2TP53 | |
| SCHEMBL365837 | 0.81 | CNR2 (0.37) | NPC1RAB9ASMN1; SMN2KMT2ACNR2 | |
| SCHEMBL365914 | 0.80 | MAPT (0.34) | S1PR3PLA2G4AACHEPARP1PABPC1 | |
| SCHEMBL365490 | 0.79 | NCEH1 (0.39) | NPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |