Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365769 | 0.92 | LTB4R (0.39) | CNR2LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL366374 | 0.91 | ALDH1A1 (0.38) | CNR2LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL366481 | 0.91 | ACHE (0.39) | PLK1NPC1RAB9ALTB4RLTB4R2 | |
| SCHEMBL365986 | 0.85 | KMT2A (0.38) | CNR2LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL365925 | 0.85 | ACHE (0.42) | — | |
| SCHEMBL366851 | 0.83 | ALDH1A1 (0.38) | CNR2KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL365593 | 0.83 | MRGPRX4 (0.39) | LTB4RLTB4R2SMN1; SMN2 | |
| SCHEMBL366612 | 0.83 | ACHE (0.38) | KMT2APLK1SMN1; SMN2 | |
| SCHEMBL365490 | 0.82 | NCEH1 (0.39) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL365915 | 0.81 | S1PR3 (0.37) | CNR2KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |