Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366080 | 0.92 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL367691 | 0.92 | ACHE (0.40) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL365986 | 0.92 | KMT2A (0.38) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL365114 | 0.90 | ALDH1A1 (0.34) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL366851 | 0.86 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL366374 | 0.86 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL365402 | 0.85 | PSEN1 (0.38) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL366618 | 0.85 | MEN1 (0.37) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL366531 | 0.84 | MEN1 (0.36) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL366815 | 0.80 | MEN1 (0.45) | KMT2AMEN1ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |