Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13787278 | 0.90 | MAPT (0.33) | PTGS1PTGS2MAPTALDH1A1HPGD | |
| SCHEMBL21543626 | 0.86 | PTGS1 (0.40) | PTGS1PTGS2MGLLFAAHMAPT | |
| SCHEMBL19575061 | 0.85 | MGLL (0.44) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL24168490 | 0.85 | CYP1A2 (0.43) | PTGS1PTGS2MGLLFAAHMAPT | |
| SCHEMBL3629996 | 0.84 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHMAPT | |
| SCHEMBL18081561 | 0.83 | PTGS1 (0.46) | PTGS1PTGS2MGLLFAAHMAPT | |
| SCHEMBL14984835 | 0.82 | PTGS1 (0.49) | PTGS1PTGS2MGLLFAAHMAPT | |
| SCHEMBL19733754 | 0.81 | MGLL (0.39) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL18090277 | 0.81 | MGLL (0.34) | PTGS1PTGS2MGLLHPGDHTT | |
| SCHEMBL18090275 | 0.81 | MGLL (0.34) | PTGS1PTGS2MGLLHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231201-B1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | GEN ELECTRIC (US) | 2018-02-14 | — | — | EP | disclosed |
| EP-2231201-B1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | GEN ELECTRIC (US) | 2018-02-14 | — | — | EP | disclosed |
| EP-2509638-B1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LTD (GB) | 2017-04-19 | — | — | EP | disclosed |
| US-20160022846-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LTD (GB) | 2016-01-28 | — | — | US | disclosed |
| US-20160022846-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LTD (GB) | 2016-01-28 | — | — | US | disclosed |
| US-20150126708-A1 | RADIOFLUORINATION METHOD | IMPERIAL INNOVATIONS LIMITED (GB) | 2015-05-07 | — | — | US | disclosed |
| US-20150126708-A1 | RADIOFLUORINATION METHOD | IMPERIAL INNOVATIONS LIMITED (GB) | 2015-05-07 | — | — | US | disclosed |
| US-8894971-B2 | Iodine radiolabelling method | GE HEALTHCARE LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8894971-B2 | Iodine radiolabelling method | GE HEALTHCARE LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| WO-2013092790-A1 | RADIOFLUORINATION METHOD | GE HEALTHCARE LIMITED (GB) | 2013-06-27 | — | — | WO | disclosed |
| EP-2591808-A2 | Selective radiolabeling of biomolecules | General Electric Company (US) | 2013-05-15 | — | — | EP | disclosed |
| US-20120237444-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2012-09-20 | — | — | US | disclosed |
| US-20120237444-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2012-09-20 | — | — | US | disclosed |
| WO-2011070136-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |
| EP-2231201-A1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | General Electric Company (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009080561-A1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | GENERAL ELECTRIC COMPANY (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080561-A1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | GENERAL ELECTRIC COMPANY (US) | 2009-07-02 | — | — | WO | disclosed |
| US-20080161537-A1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | GENERAL ELECTRIC COMPANY (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080161537-A1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | GENERAL ELECTRIC COMPANY (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080161537-A1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | GENERAL ELECTRIC COMPANY (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161537-A1 | SELECTIVE RADIOLABELING OF BIOMOLECULES | BTD, TK1, FGB | PTGS1 4771/4885PTGS2 4765/4885MGLL 2145/4885 |
| US-20160022846-A1 | IODINE RADIOLABELLING METHOD | BTD, BTN3A1, BTF3 | PTGS1 3090/4885PTGS2 3520/4885MGLL 3277/4885 |
| US-20120237444-A1 | IODINE RADIOLABELLING METHOD | BTD, BTN3A1, BTF3 | PTGS1 3090/4885PTGS2 3520/4885MGLL 3277/4885 |
| US-20150126708-A1 | RADIOFLUORINATION METHOD | BTD, RABGGTB, PFAS | PTGS1 4708/4885PTGS2 4749/4885MGLL 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.