Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632727 | 0.85 | ACHE (0.40) | — | |
| SCHEMBL3320690 | 0.79 | SIGMAR1 (0.47) | SIGMAR1POLBGRIN2B | |
| SCHEMBL3633564 | 0.77 | CYP2C9 (0.45) | CYP2C9 | |
| SCHEMBL3663846 | 0.77 | SIGMAR1 (0.47) | SIGMAR1POLBGRIN2BCYP2C9 | |
| SCHEMBL3633458 | 0.76 | HRH3 (0.39) | — | |
| SCHEMBL3322228 | 0.72 | ACHE (0.47) | SIGMAR1CYP2C9 | |
| SCHEMBL3320215 | 0.69 | CARM1 (0.48) | SIGMAR1GRIN2B | |
| SCHEMBL3627516 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL3319966 | 0.68 | ACHE (0.48) | SIGMAR1 | |
| SCHEMBL3632513 | 0.68 | CHRM1 (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155748-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008144268-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-27 | — | — | WO | disclosed |