Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666137 | 0.84 | MC4R (0.57) | ENPP2LPLLIPGSIGMAR1PRMT6 | |
| SCHEMBL17165356 | 0.83 | MC4R (0.50) | ENPP2LPLLIPGSIGMAR1PRMT6 | |
| Hydrochloric Acid SCHEMBL29953930 | 0.82 | MC4R (0.56) | ENPP2LPLLIPGSIGMAR1PRMT6 | |
| SCHEMBL3663957 | 0.82 | LPL (0.43) | LPLLIPGSIGMAR1ALDH1A1KMT2A | |
| SCHEMBL1724355 | 0.82 | SMN1; SMN2 (0.60) | ENPP2LPLLIPGPRMT6ALDH1A1 | |
| SCHEMBL29955859 | 0.81 | LPL (0.51) | ENPP2LPLLIPGSIGMAR1ALDH1A1 | |
| SCHEMBL18585928 | 0.81 | PRMT6 (0.49) | SIGMAR1PRMT6ALDH1A1KMT2AHTT | |
| SCHEMBL29955283 | 0.80 | SMN1; SMN2 (0.63) | ENPP2PRMT6ALDH1A1SMN1; SMN2CYP2D6 | |
| Hydrochloric Acid SCHEMBL29955383 | 0.80 | SMN1; SMN2 (0.58) | ENPP2LPLLIPGPRMT6ALDH1A1 | |
| SCHEMBL2248354 | 0.80 | SMN1; SMN2 (0.63) | ENPP2PRMT6ALDH1A1SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242742-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-8343966-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-01-01 | — | — | US | disclosed |
| EP-2242742-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2010-10-27 | — | — | EP | disclosed |
| US-20090215776-A1 | Organic compounds | ADCOCK CLAIRE | 2009-08-27 | — | — | US | disclosed |
| WO-2009087212-A2 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215776-A1 | Organic compounds | REN, RXFP1, MYLK | ENPP2 2108/4885LPL 4007/4885LIPG 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.