Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | CD44 | P16070 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506823 | 0.86 | OXTR (0.52) | PNMTCD44MAOBOXTRHTR2C | |
| SCHEMBL59871 | 0.84 | — | — | |
| SCHEMBL29471383 | 0.84 | — | — | |
| SCHEMBL13590042 | 0.84 | PNMT (0.65) | PNMTCD44MAOBOXTRHTR2C | |
| SCHEMBL29351494 | 0.84 | — | — | |
| SCHEMBL10612 | 0.84 | — | — | |
| Ammonia Solution, Strong SCHEMBL23320033 | 0.81 | MAOA (0.40) | MAOBOXTRHTR2C | |
| Methane SCHEMBL11147358 | 0.81 | PNMT (0.62) | PNMTCD44MAOBOXTRHTR2C | |
| SCHEMBL16439994 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL16296133 | 0.81 | PNMT (0.62) | PNMTCD44MAOBOXTRHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010082912-A1 | DERIVATIVES OF MULTI-RING AROMATIC COMPOUNDS AND USES AS ANTI-TUMOR AGENTS | AVALON PHARMACEUTICALS (US) | 2010-07-22 | — | — | WO | disclosed |
| EP-2141994-A1 | MULTI-RING COMPOUNDS AND USES THEREOF | Avalon Pharmaceuticals (US) | 2010-01-13 | — | — | EP | disclosed |
| EP-2074126-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1991233-A4 | HYDROXYPIPERIDINE DERIVATIVES AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1991233-A2 | HYDROXYPIPERIDINE DERIVATIVES AND USES THEREOF | Avalon Pharmaceuticals (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2008133975-A1 | MULTI-RING COMPOUNDS AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008049105-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |
| WO-2007098086-A2 | HYDROXYPIPERIDINE DERIVATIVES AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2007-08-30 | — | — | WO | disclosed |
| EP-1558580-A2 | N-SULFONYL-4-METHYLENEAMINO-3-HYDROXY-2-PYRIDONES AS ANTIMICROBIAL AGENTS | The Procter & Gamble Company (US) | 2005-08-03 | — | — | EP | disclosed |
| EP-1558579-A1 | N-ALKYL-4-METHYLENEAMINO-3-HYDROXY-2-PYRIDONES AS ANTIMICROBIALS | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2005016264-A2 | DIAMINE DERIVATIVES OF QUINONE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2005-02-24 | — | — | WO | disclosed |
| WO-2005011675-A1 | DERIVATIVES OF 3-HYDROXY-PYRROLE-2,4-DICARBOXYLIC ACID AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2005-02-10 | — | — | WO | disclosed |
| WO-2004043927-A1 | N-ALKYL-4-METHYLENEAMINO-3-HYDROXY-2-PYRIDONES AS ANTIMICROBIALS | THE PROCTER & GAMBLE COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043928-A2 | N-SULFONYL-4-METHYLENEAMINO-3-HYDROXY-2-PYRIDONES AS ANTIMICROBIAL AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |
| EP-1265887-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001070682-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |