Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651 | 0.91 | ALDH1A1 (0.52) | FFAR1AKR1B1PTPN1OXTRAVPR1A | |
| SCHEMBL1820 | 0.90 | FFAR1 (0.43) | FFAR1AKR1B1PTPN1OXTRAVPR1A | |
| SCHEMBL2210 | 0.90 | CTSS (0.39) | FFAR1AKR1B1PTPN1LMNAALDH1A1 | |
| SCHEMBL7278662 | 0.89 | MME (0.44) | FFAR1AKR1B1PTPN1OXTRAVPR1A | |
| SCHEMBL6509546 | 0.88 | ALDH1A1 (0.49) | FFAR1AKR1B1PTPN1OXTRAVPR1A | |
| SCHEMBL2989 | 0.88 | FFAR1 (0.43) | FFAR1AKR1B1PTPN1OXTRAVPR1A | |
| SCHEMBL2438545 | 0.87 | FFAR1 (0.48) | FFAR1AKR1B1PTPN1OXTRAVPR1A | |
| SCHEMBL3473577 | 0.87 | FFAR1 (0.46) | FFAR1AKR1B1PTPN1OXTRAVPR1A | |
| SCHEMBL3473572 | 0.87 | FFAR1 (0.46) | FFAR1AKR1B1PTPN1OXTRAVPR1A | |
| SCHEMBL1809623 | 0.85 | AGTR1 (0.54) | FFAR1AKR1B1AGTR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |