Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.39 |
| ▸ | CTSL | P07711 | 7/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSB | P07858 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664 | 0.90 | FFAR1 (0.45) | CTSSCTSLCTSKCTSBALDH1A1 | |
| SCHEMBL2441623 | 0.85 | AGTR1 (0.47) | CTSSCTSLFFAR1AKR1B1 | |
| SCHEMBL2651 | 0.81 | ALDH1A1 (0.52) | CTSSCTSLCTSKCTSBALDH1A1 | |
| SCHEMBL6016794 | 0.81 | ITGB1 (0.36) | CTSSCTSLCTSKCTSBFFAR1 | |
| SCHEMBL6016793 | 0.81 | ITGB1 (0.36) | CTSSCTSLCTSKCTSBFFAR1 | |
| SCHEMBL1820 | 0.80 | FFAR1 (0.43) | CTSSCTSLCTSKCTSBALDH1A1 | |
| SCHEMBL8476139 | 0.80 | AGTR1 (0.57) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27753418 | 0.80 | AGTR1 (0.57) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8476142 | 0.80 | AGTR1 (0.57) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2437416 | 0.79 | CTSS (0.42) | CTSSCTSLCTSKCTSBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |