Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 9/20 | 0.35 |
| ▸ | CA2 | P00918 | 9/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949205 | 0.85 | BCL2L1 (0.40) | BCL2L1CA1CA2CA4L3MBTL1 | |
| SCHEMBL4733710 | 0.84 | BCL2L1 (0.43) | BCL2L1CA1CA2CA12CA9 | |
| SCHEMBL3663913 | 0.76 | CA2 (0.42) | BCL2L1CA1CA2CA12CA9 | |
| SCHEMBL28977066 | 0.76 | BCL2L1 (0.66) | BCL2L1CA1CA2CA12CA9 | |
| SCHEMBL4735838 | 0.76 | BCL2L1 (0.45) | BCL2L1CA1CA2CA12CA9 | |
| SCHEMBL1540345 | 0.74 | CYP3A4 (0.44) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4733878 | 0.72 | BCL2L1 (0.59) | BCL2L1CA1CA2 | |
| SCHEMBL1540344 | 0.72 | CYP3A4 (0.44) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4731200 | 0.71 | BCL2L1 (0.57) | BCL2L1CA1CA2 | |
| SCHEMBL28977050 | 0.71 | BCL2L1 (0.61) | BCL2L1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231159-A1 | METHOD OF TREATING ARTHRITIS | Abbott Laboratories (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009064938-A1 | METHOD OF TREATING ARTHRITIS | ABBOTT LABORATORIES (US) | 2009-05-22 | — | — | WO | disclosed |