Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664099 | 0.85 | BCL2L1 (0.40) | BCL2L1CA2CA4CA1L3MBTL1 | |
| SCHEMBL28977050 | 0.84 | BCL2L1 (0.61) | BCL2L1CA2CA4 | |
| SCHEMBL4733710 | 0.77 | BCL2L1 (0.43) | BCL2L1CA2CA4CA1 | |
| SCHEMBL3949200 | 0.77 | MEN1 (0.40) | MEN1KMT2ACHRM2SIRT2PLK1 | |
| SCHEMBL4735838 | 0.75 | BCL2L1 (0.45) | BCL2L1CA2CA4CA1 | |
| SCHEMBL1539944 | 0.75 | CHRM2 (0.49) | MEN1KMT2ACHRM2SIRT2PLK1 | |
| SCHEMBL1539943 | 0.73 | CHRM2 (0.49) | MEN1KMT2ACHRM2SIRT2PLK1 | |
| SCHEMBL3663913 | 0.71 | CA2 (0.42) | BCL2L1MEN1KMT2ACA2CA1 | |
| SCHEMBL4733878 | 0.71 | BCL2L1 (0.59) | BCL2L1CA2CA1 | |
| SCHEMBL4731200 | 0.70 | BCL2L1 (0.57) | BCL2L1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143246-A2 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-11-26 | — | — | WO | disclosed |