Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 10/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733710 | 0.80 | BCL2L1 (0.43) | BCL2L1CA2CA1PTGES2CA9 | |
| SCHEMBL29482087 | 0.80 | BCL2L1 (0.68) | BCL2L1CA2CA1CA9CA7 | |
| SCHEMBL4733878 | 0.78 | BCL2L1 (0.59) | BCL2L1CA2CA1 | |
| SCHEMBL3663913 | 0.78 | CA2 (0.42) | BCL2L1CA2CA1PTGES2CA9 | |
| SCHEMBL4731200 | 0.77 | BCL2L1 (0.57) | BCL2L1CA2CA1 | |
| SCHEMBL19491759 | 0.76 | BCL2L1 (0.52) | BCL2L1 | |
| SCHEMBL3664099 | 0.76 | BCL2L1 (0.40) | BCL2L1CA2CA1PTGES2CA9 | |
| SCHEMBL3949205 | 0.75 | BCL2L1 (0.40) | BCL2L1CA2CA1CA4 | |
| SCHEMBL6526600 | 0.75 | CA2 (0.53) | CA2CA1PTGES2CA9CA12 | |
| SCHEMBL25773070 | 0.74 | BCL2L1 (0.51) | BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064116-A2 | METHOD OF PREVENTING OR TREATING ORGAN, HEMATOPOIETIC STEM CELL OR BONE MARROW TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | WO | disclosed |