SCHEMBL3664833

SCHEMBL3664833

CC1=Cc2c(cccc2N(c2ccccc2)c2ccccc2)C1[Si](C)(C)C1C(C)=Cc2c1cccc2N(c1ccccc1)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10053647 0.87 MEN1 (0.32)
SCHEMBL3763925 0.87 MEN1 (0.32)
SCHEMBL1454519 0.74 HTR2C (0.31)
SCHEMBL29366427 0.74 PDCD1 (0.34)
SCHEMBL61908 0.74 PDCD1 (0.34)
Hydrochloric Acid SCHEMBL3756607 0.73
SCHEMBL8369933 0.73 IDO1 (0.30)
SCHEMBL7039663 0.72 GABRA1 (0.34)
Hydrochloric Acid SCHEMBL3822639 0.72 ADRA2A (0.34)
SCHEMBL3761656 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207281-B2 Process for preparing transition metal compounds for olefins polymerization BASELL POLYOLEFINE GMBH (DE) 2012-06-26 US disclosed
US-8207281-B2 Process for preparing transition metal compounds for olefins polymerization BASELL POLYOLEFINE GMBH (DE) 2012-06-26 US disclosed
US-20100311926-A1 PROCESS FOR PREPARING TRANSITION METAL COMPOUNDS FOR OLEFINS POLYMERIZATION BASELL POLYOLEFINE GMBH (DE) 2010-12-09 US disclosed
US-20100311926-A1 PROCESS FOR PREPARING TRANSITION METAL COMPOUNDS FOR OLEFINS POLYMERIZATION BASELL POLYOLEFINE GMBH (DE) 2010-12-09 US disclosed
EP-2220101-A1 PROCESS FOR PREPARING TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION Basell Polyolefine GmbH (DE) 2010-08-25 EP disclosed
WO-2009077115-A1 PROCESS FOR PREPARING TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION BASELL POLYOLEFINE GMBH (DE) 2009-06-25 WO disclosed