Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3770222 | 0.88 | — | — | |
| SCHEMBL3664833 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL3763787 | 0.73 | MAPT (0.37) | — | |
| Hydrochloric Acid SCHEMBL27509773 | 0.71 | CYP1A2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL29564499 | 0.71 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL2525982 | 0.71 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7935429 | 0.69 | ADRA2A (0.33) | — | |
| Hydrochloric Acid SCHEMBL7144896 | 0.69 | GABRA1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL29612304 | 0.69 | GABRA1 (0.34) | — | |
| SCHEMBL3761656 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207281-B2 | Process for preparing transition metal compounds for olefins polymerization | BASELL POLYOLEFINE GMBH (DE) | 2012-06-26 | — | — | US | disclosed |
| US-20100311926-A1 | PROCESS FOR PREPARING TRANSITION METAL COMPOUNDS FOR OLEFINS POLYMERIZATION | BASELL POLYOLEFINE GMBH (DE) | 2010-12-09 | — | — | US | disclosed |