Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424728 | 0.83 | TSHR (0.73) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL16241997 | 0.75 | TSHR (0.55) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL17923896 | 0.73 | TSHR (0.61) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL26915 | 0.73 | KIF11 (0.70) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL3423876 | 0.73 | KIF11 (0.70) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL1538330 | 0.73 | TSHR (0.61) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL1367705 | 0.73 | ESR1 (0.60) | TSHRALDH1A1HPGDMAPK1ALOX15 | |
| SCHEMBL1931781 | 0.71 | KIF11 (0.67) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL11210257 | 0.71 | TSHR (0.58) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL5495871 | 0.71 | TSHR (1.00) | TSHRLMNATYRALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281046-A1 | Cyclopropanated Carbohydrates | SETON HALL UNIVERSITY | 2009-11-12 | — | — | US | claimed |
| WO-2009120390-A2 | CYCLOPROPANATED CARBOHYDRATES | SETON HALL UNIVERSITY (US) | 2009-10-01 | — | — | WO | claimed |
| EP-1196464-B9 | BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2005-03-23 | — | — | EP | claimed |
| EP-1196464-B1 | BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION | EXXON CHEMICAL PATENTS INC (US) | 2004-12-08 | — | — | EP | claimed |
| US-6506857-B2 | Di(p-trimethylsilyl-phenyl) methylene (cyclopentadienyl) (fluorenyl) hafnium dimethyl, for example; ethylene solution polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-01-14 | — | — | US | claimed |
| US-20020137959-A1 | Bridged metallocenes for olefin copolymerization | RIX FRANCIS C (US) | 2002-09-26 | — | — | US | claimed |
| EP-1196464-A1 | BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION | Exxon Chemical Patents, Inc. (US) | 2002-04-17 | — | — | EP | claimed |
| WO-2000024793-A1 | BRIDGED METALLOCENES FOR OLEFIN COPOLYMERIZATION | EXXON CHEMICAL PATENTS INC. (US) | 2000-05-04 | — | — | WO | claimed |
| EP-0045429-B1 | PROCESS FOR THE PREPARATION OF 4-TERT. BUTYLBENZALDEHYDES | BAYER AG (DE) | 1983-08-31 | — | — | EP | claimed |
| EP-0034837-B1 | P-TERT.-BUTYLBENZAL BROMIDE AND ITS DERIVATIVES SUBSTITUTED IN THE NUCLEUS BY HALOGEN | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-15 | — | — | EP | claimed |
| EP-0011281-B1 | PROCESS FOR THE PREPARATION OF P-TERT.-BUTYL BENZALDEHYDE AND THE DERIVATIVES THEREOF SUBSTITUTED IN THE NUCLEUS BY HALOGEN. | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-02-10 | — | — | EP | claimed |
| CN-112703210-B | Preparation of bimodal rubbers, thermoplastic vulcanizates, and articles made therefrom | 埃克森美孚化学专利公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-113166519-A | Blends of cyclic olefin copolymers and films made therefrom | 埃克森美孚化学专利公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-108794675-B | Process for the preparation of ethylene propylene copolymers | 埃克森美孚化学专利公司 | 2020-12-29 | — | — | CN | disclosed |
| EP-3119817-B1 | PROCESS TO PRODUCE ETHYLENE PROPYLENE COPOLYMERS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-0045429-A2 | Process for the preparation of 4-tert. butylbenzaldehydes | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
| EP-0012942-B1 | ELECTROLYTIC PROCESS FOR PRODUCING BENZALDEHYDES | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | disclosed |
| EP-0034837-A1 | P-tert.-butylbenzal bromide and its derivatives substituted in the nucleus by halogen | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0034837-A1 | P-tert.-butylbenzal bromide and its derivatives substituted in the nucleus by halogen | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0011281-A2 | Process for the preparation of p-tert.-butyl benzaldehyde and the derivatives thereof substituted in the nucleus by halogen. | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281046-A1 | Cyclopropanated Carbohydrates | GYS2, PYGB, CSGALNACT1 | TSHR 2545/4885LMNA 3369/4885TYR 1749/4885 |
| US-20020137959-A1 | Bridged metallocenes for olefin copolymerization | ERBB4, ERBB3, ERBB2 | TSHR 4790/4885LMNA 4354/4885TYR 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.