Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366073 | 0.93 | ALKBH1 (0.36) | ALDH1A1MAPTKMT2AMEN1FFAR1 | |
| SCHEMBL365786 | 0.92 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AADORA3HTR2A | |
| SCHEMBL367347 | 0.91 | KMT2A (0.38) | ALDH1A1MAPTKMT2AMEN1FFAR1 | |
| SCHEMBL365402 | 0.85 | PSEN1 (0.38) | ALDH1A1MAPTKMT2AMEN1PSEN1 | |
| SCHEMBL364641 | 0.85 | PLK1 (0.38) | ALDH1A1MAPTKMT2ASIGMAR1FFAR1 | |
| SCHEMBL366851 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AADORA3HTR2A | |
| SCHEMBL364643 | 0.84 | CYP11B1 (0.40) | ALDH1A1HTT | |
| SCHEMBL367249 | 0.84 | MEN1 (0.36) | MAPTKMT2AMEN1PSEN1PSEN2 | |
| SCHEMBL365106 | 0.82 | KMT2A (0.39) | ALDH1A1MAPTKMT2AMEN1PSEN1 | |
| SCHEMBL366564 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AADORA3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |