Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HK1 | P19367 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366073 | 0.92 | ALKBH1 (0.36) | SMN1; SMN2ALDH1A1HK1HKDC1KMT2A | |
| SCHEMBL365786 | 0.92 | ALDH1A1 (0.38) | ALDH1A1KMT2AFFAR1SIGMAR1PSEN1 | |
| SCHEMBL366016 | 0.90 | MAPK12 (0.39) | SMN1; SMN2CNR1CNR2 | |
| SCHEMBL367249 | 0.90 | MEN1 (0.36) | HTR6KMT2APSEN1PSEN2APH1B | |
| SCHEMBL367225 | 0.86 | KMT2A (0.40) | PLK1SMN1; SMN2ALDH1A1KMT2ACNR1 | |
| SCHEMBL366565 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KMT2AFFAR1SIGMAR1PSEN1 | |
| SCHEMBL366612 | 0.84 | ACHE (0.38) | PLK1DRD2HTR6SMN1; SMN2KMT2A | |
| SCHEMBL364643 | 0.84 | CYP11B1 (0.40) | ALDH1A1CNR2 | |
| SCHEMBL367347 | 0.84 | KMT2A (0.38) | HTR6SMN1; SMN2ALDH1A1KMT2AFFAR1 | |
| SCHEMBL365103 | 0.83 | MAPT (0.38) | SMN1; SMN2ALDH1A1KMT2APSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |