Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSHR | P23945 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666582 | 0.90 | EPHX2 (0.44) | FSHREPHX2ALDH1A1CA1CA2 | |
| SCHEMBL3674765 | 0.90 | FSHR (0.42) | FSHREPHX2ALDH1A1CA1CA2 | |
| SCHEMBL3671754 | 0.90 | FSHR (0.47) | FSHRHPGDEPHX2ALDH1A1CA1 | |
| SCHEMBL3666210 | 0.88 | FSHR (0.40) | FSHREPHX2PPARA | |
| SCHEMBL1950346 | 0.87 | PTGDR2 (0.47) | FSHR | |
| SCHEMBL1948540 | 0.80 | FSHR (0.46) | FSHRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1949617 | 0.80 | CTSL (0.44) | FSHREPHX2ALDH1A1GAAMTNR1A | |
| SCHEMBL3665828 | 0.79 | FSHR (0.38) | FSHRTRPV1PPARA | |
| SCHEMBL1948087 | 0.77 | PTGDR2 (0.47) | FSHREPHX2ALDH1A1PPARA | |
| SCHEMBL3663870 | 0.77 | HDAC1 (0.45) | HPGDALDH1A1CA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | claimed |
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |