Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSHR | P23945 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666427 | 0.90 | FSHR (0.42) | FSHRALDH1A1EPHX2CA1CA2 | |
| SCHEMBL3666582 | 0.90 | EPHX2 (0.44) | FSHRALDH1A1EPHX2CA1CA2 | |
| SCHEMBL3671754 | 0.89 | FSHR (0.47) | FSHRALDH1A1EPHX2CA1CA2 | |
| SCHEMBL3666210 | 0.89 | FSHR (0.40) | FSHREPHX2THRATHRBHDAC1 | |
| SCHEMBL1948540 | 0.81 | FSHR (0.46) | FSHRALDH1A1GYS1GAA | |
| SCHEMBL3665828 | 0.80 | FSHR (0.38) | FSHRTHRATHRB | |
| SCHEMBL1949617 | 0.79 | CTSL (0.44) | FSHRALDH1A1EPHX2GAAHDAC1 | |
| SCHEMBL1950346 | 0.77 | PTGDR2 (0.47) | FSHRGYS1 | |
| SCHEMBL1948087 | 0.77 | PTGDR2 (0.47) | FSHRALDH1A1EPHX2GYS1 | |
| SCHEMBL1946723 | 0.77 | PTGDR2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |