Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931701 | 0.76 | APLNR (0.43) | APLNRMIF | |
| SCHEMBL2912718 | 0.72 | DAO (0.34) | — | |
| SCHEMBL30525684 | 0.72 | APLNR (0.32) | APLNRMIF | |
| SCHEMBL28261083 | 0.65 | PLAU (0.54) | MIF | |
| SCHEMBL557845 | 0.65 | PLAU (0.53) | — | |
| SCHEMBL7388303 | 0.65 | APLNR (0.58) | APLNRMIF | |
| SCHEMBL1661864 | 0.65 | CRHBP (0.39) | MIF | |
| SCHEMBL384468 | 0.64 | APLNR (0.43) | APLNRMIF | |
| SCHEMBL29435535 | 0.64 | PLAU (0.52) | APLNRMIF | |
| SCHEMBL3223751 | 0.64 | APLNR (0.43) | APLNRMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240485-A1 | TRICYCLIC COMPOUNDS HAVING CORTICOTROPIN-RELEASING FACTOR ANTAGONISTIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Pharmaceutical Company Limited (JP) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009093747-A1 | TRICYCLIC COMPOUNDS HAVING CORTICOTROPIN-RELEASING FACTOR ANTAGONISTIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-07-30 | — | — | WO | disclosed |
| US-4224331-A | TREATING GASTRIC ULCERS AND REDUCING GASTRIC ACID SECRETION | BEECHAM GROUP LIMITED (GB) | 1980-09-23 | — | — | US | disclosed |