SCHEMBL36672

SCHEMBL36672

C=C(Cc1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.64
ABCC4 O15439 1/20 0.64
GAA P10253 1/20 0.64
TSHR P16473 1/20 0.64
PTGS1 P23219 1/20 0.64
HTT P42858 1/20 0.64
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
ALDH1A1 P00352 4/20 0.51
FFAR1 O14842 2/20 0.50
HPGD P15428 2/20 0.49
MAPT P10636 2/20 0.46
NR1H4 Q96RI1 1/20 0.46
SRR Q9GZT4 1/20 0.46
PSAT1 Q9Y617 1/20 0.46
SRD5A2 P31213 1/20 0.46
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8692226 0.98 LMNA (0.62) LMNAABCC4GAATSHRPTGS1
SCHEMBL2732935 0.94 LMNA (0.54) LMNAABCC4GAATSHRPTGS1
SCHEMBL41907 0.87 CES1 (0.58) LMNAABCC4GAATSHRPTGS1
SCHEMBL3426193 0.87 CA2 (0.46) LMNAABCC4GAATSHRPTGS1
Bromide SCHEMBL11497452 0.85 CES1 (0.56) LMNAABCC4GAATSHRPTGS1
Hydrochloric Acid SCHEMBL27862997 0.85 CES1 (0.56) LMNAABCC4GAATSHRPTGS1
SCHEMBL27564061 0.85 CES1 (0.56) LMNAABCC4GAATSHRPTGS1
SCHEMBL8692222 0.85 LMNA (0.60) LMNAABCC4GAATSHRPTGS1
SCHEMBL4806417 0.85 CTBP2 (0.51) LMNAABCC4GAATSHRPTGS1
SCHEMBL4808967 0.85 CTBP2 (0.51) LMNAABCC4GAATSHRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4073080-B1 PROCESS FOR INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL)METHYL)PROPANOYL)-L-ALANINE KOS THERAPEUTICS INC (US) 2023-10-11 EP claimed
US-20230041504-A1 METHOD FOR THE INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL) METHYL)PROPANOYL)-L-ALANINE KOS THERAPEUTICS, INC. 2023-02-09 US claimed
CN-114787171-A Industrial process for the preparation of the disodium salt of ((2S) -3- ([1, 1' -biphenyl ] -4-yl) -2- ((hydroxy ((1R) -1- (((1- (isobutyroyloxy) ethoxy) carbonyl) amino) ethyl) phosphoryl) methyl) propionyl) -L-alanine 领先药物公司 2022-07-22 CN claimed
WO-2021116617-A1 PROCESS FOR INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL)METHYL)PROPANOYL)-L-ALANINE PHARMALEADS (FR) 2021-06-17 WO claimed
US-20090017195-A1 CURABLE ENCAPSULANT COMPOSITION AND ASSOCIATED METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2009-01-15 US claimed
EP-1831285-A1 CURABLE ENCAPSULANT COMPOSITION AND METHOD FOR PREPARING IT General Electric Company (US) 2007-09-12 EP claimed
WO-2006068728-A1 CURABLE ENCAPSULANT COMPOSITION AND METHOD FOR PREPARING IT GENERAL ELECTRIC COMPANY (US) 2006-06-29 WO claimed
US-20060135705-A1 melting at least a portion of pellets or powder, the portion comprising a mixture of a functionalized polymer and a reactive monomer andflowing the molten portion into contact with the portion of the electronic or optical device GENERAL ELECTRIC COMPANY 2006-06-22 US claimed
US-5549807-A Thermoplastic composites formed by electropolymerization of N-substituted methacrylamide monomers THE UNIVERSITY OF CONNECTICUT (US) 1996-08-27 US claimed
US-5238542-A Onto electrically conductive filler THE UNIVERSITY OF CONNECTICUT (US) 1993-08-24 US claimed
EP-0407773-A2 Improved holographic notch filters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-16 EP claimed
EP-0404099-A2 Improved holographic optical combiners for head-up displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-12-27 EP claimed
EP-0404098-A2 Holographic optical elements having a reflection hologram formed in a photopolymer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-12-27 EP claimed
US-4965152-A PHOTOPOLYMER FILMS IMAGED TO CONTAIN REFLECTION MIRROR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-23 US claimed
US-4950567-A Holographic optical combiners for head-up displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-21 US claimed
US-4942102-A MULTILAYER OPTICAL ELEMENT, BINDER OF POLYVINYL ACETAL, AN UNSATURATED MONOMER AND A PHOTOINITIATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-17 US claimed
EP-3216838-B1 COMPOSITE SYSTEM WITH MASKING MATERIAL HAVING LOW ADHESION TESA SE (DE) 2026-04-01 EP disclosed
WO-2026047156-A1 POLY(METH)ACRYLATES, PRESSURE-SENSITIVE ADHESIVE COMPOUNDS, AND METHOD FOR THE PRODUCTION THEREOF TESA SE (DE) 2026-03-05 WO disclosed
EP-0254032-A2 Neutral metalloendopeptidase inhibitors in the treatment of hypertension SCHERING CORPORATION (US) 1988-01-27 EP disclosed
EP-0212440-A2 Radiation-sensitive composition, registration material containing such a composition and process for the production of relief images HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230041504-A1 METHOD FOR THE INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL) METHYL)PROPANOYL)-L-ALANINE CHAMP1, AADAT, PTMS LMNA 2343/4885ABCC4 3820/4885GAA 1354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.