Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21582021 | 0.94 | TSHR (0.52) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL18980394 | 0.84 | ALDH1A1 (0.48) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL671326 | 0.83 | TSHR (0.52) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL2408682 | 0.81 | DPP4 (0.52) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL29941102 | 0.81 | DPP4 (0.52) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL10964869 | 0.81 | KMT2A (0.37) | TSHRSMN1; SMN2KDM4ERAB9ACYP3A4 | |
| SCHEMBL29886586 | 0.79 | TSHR (0.64) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL432644 | 0.79 | TSHR (0.64) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL7778429 | 0.79 | CYP3A4 (0.46) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL3358680 | 0.79 | G6PD (0.42) | TSHRALDH1A1TP53CASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996339-A | Colorless | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-26 | — | — | US | claimed |
| WO-2026098107-A1 | FUSED HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION THEREOF AND USE THEREOF | 青岛清原化合物有限公司 | 2026-05-15 | — | — | WO | disclosed |
| US-12503467-B2 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors | IDEAYA BIOSCIENCES, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| CN-119528824-A | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-111699176-B | Quinazolinones as PARP14 inhibitors | 里邦医疗公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-111630036-B | Oxoacetylacetic acid derivatives and methods of use thereof | 西利康斯瓦特股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-113166078-B | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2024-11-19 | — | — | CN | disclosed |
| WO-2024208143-A1 | TRIAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2024-10-10 | — | — | WO | disclosed |
| WO-2024169666-A1 | BENZENE RING-SUBSTITUTED PYRIMIDINE CARBOXYLIC ACID COMPOUND, AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 青岛清原化合物有限公司 | 2024-08-22 | — | — | WO | disclosed |
| US-11958837-B2 | Quinazolinones as PARP14 inhibitors | RIBON THERAPEUTICS, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| EP-0560482-B1 | 4-Benzoyl isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-08-06 | — | — | EP | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| CN-1149291-A | Formylaminophenylsulphonyl ureas, method of preparing them and their use as herbicides and plant-growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1997-05-07 | — | — | CN | disclosed |
| CN-1149290-A | Phenylsulfonyl ureas with nitrogen substituents, method for their preparation and use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1997-05-07 | — | — | CN | disclosed |
| EP-0734380-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016678-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-06-22 | — | — | WO | disclosed |
| EP-0560482-A1 | 4-Benzoyl isoxazoles derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-09-15 | — | — | EP | disclosed |
| US-4355127-A | Physical property improvement in nitrile resins by use of certain processing aids and fillers | SOHIO (US) | 1982-10-19 | — | — | US | disclosed |
| US-4292228-A | MOLDING MATERIALS COMPRISING A NITRILE-ESTER-CONJUGATED DIENE ADDITION POLYMER, AN ANHYDRIDE, AND AN INORGANIC COMPOUND | THE STANDARD OIL COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11958837-B2 | Quinazolinones as PARP14 inhibitors | PARP14, PARP15, PARP11 | TSHR 4683/4885ALDH1A1 2388/4885TP53 215/4885 |
| US-12503467-B2 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors | MAT2B, MAT2A, MAT1A | TSHR 3845/4885ALDH1A1 910/4885TP53 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.