Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366079 | 0.92 | KDM4E (0.42) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL367690 | 0.92 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL365985 | 0.92 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL365113 | 0.90 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL366850 | 0.86 | MAPT (0.37) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL366373 | 0.86 | MAPT (0.37) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL366617 | 0.85 | MEN1 (0.45) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL365401 | 0.84 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL366530 | 0.81 | CYP11B1 (0.35) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL366816 | 0.80 | KMT2A (0.37) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |