Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366806 | 0.93 | ALDH1A1 (0.35) | ALDH1A1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL366905 | 0.86 | KDM4E (0.37) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL366072 | 0.82 | FFAR1 (0.37) | ALDH1A1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL366831 | 0.81 | MCL1 (0.35) | ALDH1A1KMT2AMEN1MCL1BCL2 | |
| SCHEMBL365105 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL364642 | 0.80 | CYP11B1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL366564 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL367346 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL367193 | 0.76 | GPR132 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL364640 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KMT2AMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |