SCHEMBL3669749

SCHEMBL3669749

CCc1ccc(O)c(/C=C/c2ccccc2C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 3/20 0.52
USP2 O75604 2/20 0.52
GAA P10253 2/20 0.52
MAPT P10636 2/20 0.52
ALOX12 P18054 2/20 0.52
HTT P42858 2/20 0.52
HSD17B10 Q99714 2/20 0.52
ALOX15 P16050 1/20 0.52
POLB P06746 2/20 0.51
PSMD14 O00487 1/20 0.51
TRPA1 O75762 2/20 0.47
ALOX5 P09917 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
RAB9A P51151 2/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
CYP1A2 P05177 2/20 0.38
ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4530034 0.83 GABRA1 (0.49) KDM4EALDH1A1USP2GAAMAPT
SCHEMBL6054800 0.82 TRPA1 (0.55) KDM4EALDH1A1USP2GAAMAPT
SCHEMBL9495150 0.80 SNCA (0.48) KDM4EALDH1A1GAAMAPTHSD17B10
SCHEMBL3668133 0.80 ALOX5 (0.50) KDM4EALDH1A1GAAMAPTALOX12
SCHEMBL28738145 0.78 TRPA1 (0.55) KDM4EALDH1A1USP2GAAMAPT
SCHEMBL7838928 0.77 ABL1 (0.53) KDM4EALDH1A1GAAMAPTHSD17B10
SCHEMBL27477000 0.77 TRPA1 (0.59) KDM4EALDH1A1MAPTHTTTRPA1
SCHEMBL21467261 0.73 ALDH1A1 (0.51) KDM4EALDH1A1USP2GAAMAPT
SCHEMBL14071585 0.73 TRPA1 (0.50) KDM4EALDH1A1USP2GAAMAPT
SCHEMBL23491306 0.72 TRPA1 (0.63) KDM4EALDH1A1USP2GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2162518-A1 LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT CHEMTURA CORPORATION (US) 2010-03-17 EP disclosed
WO-2009009293-A1 LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT CHEMTURA CORPORATION (US) 2009-01-15 WO disclosed
US-20090011961-A1 Lubricant compositions stabilized with styrenated phenolic antioxidant CROMPTON HOLDING CORPORATION 2009-01-08 US disclosed