Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | DBH | P09172 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172415 | 0.83 | KDM4E (0.71) | KDM4EDBHGAARECQLHTT | |
| SCHEMBL10026169 | 0.83 | ALDH1A1 (0.49) | KDM4EDBHGAARECQLCES2 | |
| SCHEMBL23646742 | 0.83 | SMN1; SMN2 (0.48) | KDM4EDBHGAARECQLCES2 | |
| SCHEMBL15822168 | 0.82 | KDM4E (0.53) | KDM4EDBHGAARECQLSMN1; SMN2 | |
| SCHEMBL16689552 | 0.82 | HDAC1 (0.58) | KDM4EDBHGAARECQLCES2 | |
| SCHEMBL27941549 | 0.82 | CES2 (0.52) | KDM4EDBHGAARECQLCES2 | |
| SCHEMBL879752 | 0.82 | CHRNA1 (0.64) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL8745697 | 0.82 | KDM4E (0.53) | KDM4EDBHGAARECQLCES2 | |
| SCHEMBL12780290 | 0.82 | GAA (0.53) | KDM4EDBHGAARECQLCES2 | |
| SCHEMBL2237695 | 0.82 | GAA (0.53) | KDM4EDBHGAARECQLTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023022042-A1 | PHOTOSENSITIVE SURFACE TREATMENT AGENT, LAMINATE, TRANSISTOR, PATTERN FORMATION METHOD, AND TRANSISTOR MANUFACTURING METHOD | 株式会社ニコン | 2023-02-23 | — | — | WO | disclosed |
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN (DE) | 2020-06-04 | — | — | US | disclosed |
| WO-2017123860-A1 | SPIROHEPTANE SALICYLAMIDES AND RELATED COMPOUNDS AS INHIBITORS OF ROCK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-20 | — | — | WO | disclosed |
| EP-3016926-B1 | METHOD OF ACYLATING AN AROMATIC COMPOUND | DSM IP ASSETS BV (NL) | 2017-05-31 | — | — | EP | disclosed |
| US-20160185699-A1 | METHOD OF ACYLATING AN AROMATIC COMPOUND | DSM IP ASSETS B.V. (NL) | 2016-06-30 | — | — | US | disclosed |
| EP-3016926-A1 | METHOD OF ACYLATING AN AROMATIC COMPOUND | DSM IP Assets B.V. (NL) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015001032-A1 | METHOD OF ACYLATING AN AROMATIC COMPOUND | DSM IP ASSETS B.V. (NL) | 2015-01-08 | — | — | WO | disclosed |
| US-8497361-B2 | Topoisomerase binding probe and method of use | SRI INTERNATIONAL (US) | 2013-07-30 | — | — | US | disclosed |
| US-20120225788-A1 | Topoisomerase Binding Probe and Method of Use | SRI INTERNATIONAL | 2012-09-06 | — | — | US | disclosed |
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |
| EP-0273647-B1 | COUMARAN DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-4857516-A | Coumaran derivatives and their pharmaceutical use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0273647-A1 | Coumaran derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |
| EP-0079372-B1 | PRIMED INORGANIC SUBSTRATES OVERCOATED WITH CURABLE PROTECTIVE COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-10-08 | — | — | EP | disclosed |
| US-4182730-A | Process for the preparation of substituted dihydrocinnamaldehydes via novel β-chlorocinnamaldehydes | GIVAUDAN CORPORATION (US) | 1980-01-08 | — | — | US | disclosed |
| US-4116665-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185699-A1 | METHOD OF ACYLATING AN AROMATIC COMPOUND | ARSA, ACR, APEH | KDM4E 129/4885DBH 714/4885GAA 71/4885 |
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | NR1H4, NR1H3, NR1H2 | KDM4E 2277/4885DBH 408/4885GAA 2055/4885 |
| US-20120225788-A1 | Topoisomerase Binding Probe and Method of Use | TOP2B, TOP1, TOP2A | KDM4E 742/4885DBH 3768/4885GAA 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.