Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.40 |
| ▸ | WEE1 | P30291 | 4/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135332 | 0.82 | GSK3B (0.56) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL29032840 | 0.81 | GSK3B (0.54) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| Ammonia Solution, Strong SCHEMBL28821133 | 0.81 | GSK3B (0.54) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL52297 | 0.78 | HDAC4 (0.41) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL29589906 | 0.78 | HDAC4 (0.41) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL5616554 | 0.76 | GSK3B (0.52) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9555614 | 0.73 | GSK3B (0.67) | GSK3BTDP2MEN1KMT2ALMNA | |
| SCHEMBL9016868 | 0.71 | GSK3B (0.50) | GSK3BWEE1CHEK1TDP2MEN1 | |
| SCHEMBL9110123 | 0.70 | MAOA (0.57) | HDAC4HDAC2HDAC8HDAC6PARP10 | |
| SCHEMBL18436648 | 0.70 | FLT3 (0.41) | HNF4AHDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106810482-B | A kind of 3- phenylseleno -1- acetone derivatives and its synthetic method | 中国科学院大连化学物理研究所 | 2019-02-15 | — | — | CN | claimed |
| CN-106810482-A | A kind of 3- phenylselenos -1- acetone derivatives and its synthetic method | 中国科学院大连化学物理研究所 | 2017-06-09 | — | — | CN | claimed |
| CN-106810482-B | A kind of 3- phenylseleno -1- acetone derivatives and its synthetic method | 中国科学院大连化学物理研究所 | 2019-02-15 | — | — | CN | disclosed |
| EP-3224261-A1 | OPIOID RECEPTOR MODULATORS | The Trustees of Columbia University in the City of New York (US) | 2017-10-04 | — | — | EP | disclosed |
| CN-106810482-A | A kind of 3- phenylselenos -1- acetone derivatives and its synthetic method | 中国科学院大连化学物理研究所 | 2017-06-09 | — | — | CN | disclosed |
| WO-2016086158-A1 | OPIOID RECEPTOR MODULATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-06-02 | — | — | WO | disclosed |
| EP-2139859-A1 | DECHALCOGENATIVE METHODS FOR THE PREPARATION OF ALLYLIC SULFIDES | The Board Of Trustees Of The University Of Illinois (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008134058-A1 | DECHALCOGENATIVE METHODS FOR THE PREPARATION OF ALLYLIC SULFIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-11-06 | — | — | WO | disclosed |
| EP-0815111-B1 | ANALOGUES OF N-ACETYLARDEEMIN, METHOD OF PREPARATION AND USES THEREOF | UNIV COLUMBIA (US) | 2007-10-10 | — | — | EP | disclosed |
| EP-0815111-A4 | ANALOGUES OF N-ACETYLARDEEMIN, METHOD OF PREPARATION AND USES THEREOF | UNIV COLUMBIA (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0815111-A1 | ANALOGUES OF N-ACETYLARDEEMIN, METHOD OF PREPARATION AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997018215-A9 | ANALOGUES OF N-ACETYLARDEEMIN, METHOD OF PREPARATION AND USES THEREOF | — | 1997-11-06 | — | — | WO | disclosed |
| EP-0766685-A4 | ARYL, ALKYL, ALKENYL, AND ALKYNYLMACROLIDES | MERCK & CO INC (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997018215-A1 | ANALOGUES OF N-ACETYLARDEEMIN, METHOD OF PREPARATION AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-05-22 | — | — | WO | disclosed |
| EP-0766685-A1 | ARYL, ALKYL, ALKENYL, AND ALKYNYLMACROLIDES | MERCK & CO. INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1997005160-A1 | BICYCLIC LACTAM DERIVATIVES AS THROMBIN INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1997-02-13 | — | — | WO | disclosed |
| WO-1995034568-A1 | ARYL, ALKYL, ALKENYL, AND ALKYNYLMACROLIDES | MERCK & CO., INC. (US) | 1995-12-21 | — | — | WO | disclosed |