Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675473 | 0.80 | AR (0.42) | GAAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL3675112 | 0.76 | DAO (0.41) | ALDH1A1MAPTHPGDHTT | |
| SCHEMBL28342480 | 0.74 | DAO (0.34) | MAPT | |
| SCHEMBL1133787 | 0.73 | GSK3B (0.34) | MAPTKMT2AMEN1LMNA | |
| SCHEMBL1334773 | 0.72 | GSK3A (0.32) | — | |
| SCHEMBL3299248 | 0.72 | PYCR1 (0.47) | GAANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9508340 | 0.69 | MAOA (0.35) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL2479846 | 0.68 | GAA (0.46) | GAAMAPTKMT2AMEN1ROS1 | |
| SCHEMBL549018 | 0.67 | MAOA (0.35) | KMT2AMEN1 | |
| SCHEMBL19439526 | 0.67 | DAO (0.44) | GAAKDM4EALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825188-B2 | Thermoplastic elastomer with acyloxyphenyl hard block segment | DESIGNER MOLECULES, INC. (US) | 2010-11-02 | — | — | US | claimed |
| WO-2008077141-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2008-06-26 | — | — | WO | claimed |
| US-20080146738-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2008-06-19 | — | — | US | claimed |
| US-7825188-B2 | Thermoplastic elastomer with acyloxyphenyl hard block segment | DESIGNER MOLECULES, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| WO-2008077141-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080146738-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2008-06-19 | — | — | US | disclosed |