SCHEMBL549018

SCHEMBL549018

O=C1C=C(Cc2cccc(CC3=CC(=O)NC3=O)c2)C(=O)N1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.35
MAOB P27338 4/20 0.35
TGM2 P21980 1/20 0.34
PTPN1 P18031 1/20 0.33
DAO P14920 4/20 0.33
PARP11 Q9NR21 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3729851 0.88 DAO (0.48) DAOMEN1KMT2A
SCHEMBL4079372 0.88 DAO (0.48) MAOAMAOBDAO
SCHEMBL94148 0.86 MAOA (0.48) MAOAMAOBPTPN1DAOMEN1
Ammonia Solution, Strong SCHEMBL27962960 0.85 MAOA (0.47) MAOAMAOBPTPN1DAOMEN1
SCHEMBL9508340 0.84 MAOA (0.35) MAOAMAOBTGM2PTPN1MEN1
Ethylene SCHEMBL28271283 0.83 MAOA (0.46) MAOAMAOBPTPN1DAOMEN1
SCHEMBL1316857 0.83 MAOA (0.39) MAOAMAOBDAOMEN1KMT2A
SCHEMBL18972987 0.82 TDP2 (0.38)
SCHEMBL18972983 0.82 AGXT (0.46)
SCHEMBL27537281 0.80 MAOA (0.47) MAOAMAOBPTPN1DAOMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent SIKA TECHNOLOGY AG (CH) 2026-02-17 US claimed
CN-114096598-B Thermally expandable composition comprising a chemical blowing agent SIKA技术股份公司 2023-10-31 CN claimed
EP-3632941-B1 RESIN COMPOSITION CUBICURE GMBH (AT) 2023-08-23 EP claimed
US-20220372238-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2022-11-24 US claimed
EP-3861037-B1 RESIN COMPOSITION CUBICURE GMBH (AT) 2022-10-19 EP claimed
EP-4013810-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT Sika Technology AG (CH) 2022-06-22 EP claimed
CN-113845775-B Preparation method of hyperbranched polymer modified boron nitride heat-conducting and insulating composite material 江南大学 2022-06-21 CN claimed
CN-114096598-A Thermally expandable composition comprising a chemical blowing agent SIKA技术股份公司 2022-02-25 CN claimed
CN-113845775-A Preparation method of hyperbranched polymer modified boron nitride heat-conducting and insulating composite material 江南大学 2021-12-28 CN claimed
US-20210395420-A1 RESIN COMPOSITION CUBICURE GMBH (AT) 2021-12-23 US claimed
EP-3861037-A1 RESIN COMPOSITION Cubicure GmbH (AT) 2021-08-11 EP claimed
WO-2020070639-A1 RESIN COMPOSITION CUBICURE GMBH (AT) 2020-04-09 WO claimed
EP-3632941-A1 RESIN COMPOSITION Cubicure GmbH (AT) 2020-04-08 EP claimed
EP-2978794-B1 CURABLE MIXTURES BASED ON XYLYLENE BISMALEIMIDE EVONIK DEGUSSA GMBH (DE) 2017-05-03 EP claimed
EP-0212808-B1 Curable resins TECHNOCHEMIE GMBH (DE) 1993-11-24 EP claimed
EP-0230741-B1 CURABLE RESINS Technochemie GmbH - Verfahrenstechnik (DE) 1993-08-11 EP claimed
EP-0230741-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-08-05 EP claimed
JP-4202252-A None JP disclosed
EP-0012715-A1 Epoxide resin/beta-aminocrotonic acid derivative compositions which are heat curable and stable when stored, and the manufacture of insoluble and unmeltable plastic products therefrom CIBA-GEIGY AG (CH) 1980-06-25 EP disclosed
US-4110364-A AND BISMALEIIMIDES MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1978-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent CA1, CA3, CA12 MAOA 857/4885MAOB 1874/4885TGM2 2032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.