SCHEMBL3671582

SCHEMBL3671582

O=S(=O)(c1ccc(Cl)cc1-c1ccc(F)cc1)c1ccc(Cl)cc1-c1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.46
PTGS1 P23219 2/20 0.41
FABP4 P15090 2/20 0.40
P2RX1 P51575 1/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
S100A4 P26447 1/20 0.39
CCR2 P41597 1/20 0.39
GRM5 P41594 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446544 0.89 GRM5 (0.44) PTGS2PTGS1CCR2GRM5
SCHEMBL10977080 0.89 S100A4 (0.45) PTGS2PTGS1S100A4CCR2
SCHEMBL11340874 0.82 POLB (0.44) FABP4SMN1; SMN2S100A4
SCHEMBL3039623 0.81 S100A4 (0.46) PTGS2PTGS1KDM4ES100A4GABRP
SCHEMBL612087 0.79 ADRA1D (0.41) S100A4CCR2GRM5
SCHEMBL9469098 0.79 KDM4E (0.45) PTGS2PTGS1KDM4ENPC1RAB9A
SCHEMBL3446022 0.78 GABRP (0.43) CCR2GRM5GABRPGABRDGABRA1
SCHEMBL20904953 0.77 NPC1 (0.46) PTGS2PTGS1FABP4P2RX1KDM4E
SCHEMBL31067176 0.77 NPC1 (0.46) PTGS2PTGS1FABP4P2RX1KDM4E
SCHEMBL3446869 0.76 PGR (0.43) RAB9AS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-7449132-B2 Proton conductive composition and proton conductive membrane JSR CORPORATION (JP) 2008-11-11 US disclosed
CN-100339414-C Sulfonic group-containing polyarylene block copolymer, process for production thereof, solid polymer electrolyte and proton conductive membrane JSR CORP (JP) 2007-09-26 CN disclosed
EP-1400548-B1 Novel aromatic sulfonic acid ester derivative, polyarylene, polyarylene having sulfonic acid group and process for producing the same, and polymer solid electrolyte and proton-conductive membrane JSR CORP (JP) 2007-07-11 EP disclosed
US-7163988-B2 Aromatic sulfonic acid ester derivative, polyarylene, polyarylene having sulfonic acid group and process for producing the same, and polymer solid electrolyte and proton-conductive membrane JSR CORPORATION (JP) 2007-01-16 US disclosed
CN-1237041-C Halogenated aromatic compound, its polymer, and proton conductive membrane containing same JSR CORP (JP) 2006-01-18 CN disclosed
US-20050116206-A1 Proton conductive composition and proton conductive membrane JSR CORPORATION 2005-06-02 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
EP-1400548-A1 Novel aromatic sulfonic acid ester derivative, polyarylene, polyarylene having sulfonic acid group and process for producing the same, and polymer solid electrolyte and proton-conductive membrane JSR Corporation (JP) 2004-03-24 EP disclosed
US-20040044166-A1 Novel aromatic sulfonic acid ester derivative, polyarylene, polyarylene having sulfonic acid group and process for producing the same, and polymer solid electrolyte and proton-conductive membrane JSR CORPORATION (JP) 2004-03-04 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
CN-1379010-A Halogenated aromatic compound, its polymer, and proton conductive membrane containing same JSR CORP (JP) 2002-11-13 CN disclosed